KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CREBBP
All Species:
24.24
Human Site:
S566
Identified Species:
44.44
UniProt:
Q92793
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92793
NP_001073315.1
2442
265351
S566
N
P
L
M
N
D
G
S
N
S
G
N
I
G
T
Chimpanzee
Pan troglodytes
XP_523285
2442
265358
S566
N
P
L
M
N
D
G
S
N
S
G
N
I
G
T
Rhesus Macaque
Macaca mulatta
XP_001095225
2442
265320
S566
N
P
L
M
N
D
G
S
N
S
G
N
I
G
T
Dog
Lupus familis
XP_851777
2404
260682
P544
S
T
L
P
T
A
A
P
P
S
G
T
G
V
R
Cat
Felis silvestris
Mouse
Mus musculus
P45481
2441
265456
S565
N
P
L
M
N
D
G
S
N
S
G
N
I
G
S
Rat
Rattus norvegicus
NP_596872
2444
265618
S565
N
P
L
M
N
D
G
S
N
S
G
S
I
G
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_414964
2447
266615
T554
N
P
L
M
N
D
G
T
N
S
G
N
V
G
N
Frog
Xenopus laevis
NP_001088637
2428
264402
N550
N
S
L
L
S
D
G
N
S
P
S
T
V
G
N
Zebra Danio
Brachydanio rerio
NP_001082924
2111
234059
S464
A
M
S
N
V
P
M
S
Q
A
P
M
G
T
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524642
3276
340709
N917
N
A
G
N
P
N
Q
N
A
G
G
V
A
G
G
Honey Bee
Apis mellifera
XP_001122031
2606
284119
R698
L
S
V
P
N
E
N
R
L
A
N
L
Q
L
P
Nematode Worm
Caenorhab. elegans
P34545
2056
227161
Q409
K
R
K
L
I
Q
Q
Q
L
V
L
L
L
H
A
Sea Urchin
Strong. purpuratus
XP_782558
2635
288594
S786
S
N
V
P
P
A
S
S
F
Q
G
M
N
S
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
99.4
93.9
N.A.
94.8
95.8
N.A.
N.A.
88
76
61.5
N.A.
36.5
42.7
30.5
38.5
Protein Similarity:
100
99.9
99.6
95.5
N.A.
96.4
97.2
N.A.
N.A.
92
83.3
68.8
N.A.
46.7
54.7
43.9
50.9
P-Site Identity:
100
100
100
20
N.A.
93.3
86.6
N.A.
N.A.
80
33.3
6.6
N.A.
20
6.6
0
13.3
P-Site Similarity:
100
100
100
26.6
N.A.
100
100
N.A.
N.A.
93.3
66.6
13.3
N.A.
33.3
26.6
13.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
0
16
8
0
8
16
0
0
8
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
54
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% F
% Gly:
0
0
8
0
0
0
54
0
0
8
70
0
16
62
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
0
0
0
0
8
0
0
0
0
0
0
0
39
0
0
% I
% Lys:
8
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
8
0
62
16
0
0
0
0
16
0
8
16
8
8
8
% L
% Met:
0
8
0
47
0
0
8
0
0
0
0
16
0
0
0
% M
% Asn:
62
8
0
16
54
8
8
16
47
0
8
39
8
0
16
% N
% Pro:
0
47
0
24
16
8
0
8
8
8
8
0
0
0
8
% P
% Gln:
0
0
0
0
0
8
16
8
8
8
0
0
8
0
0
% Q
% Arg:
0
8
0
0
0
0
0
8
0
0
0
0
0
0
16
% R
% Ser:
16
16
8
0
8
0
8
54
8
54
8
8
0
8
16
% S
% Thr:
0
8
0
0
8
0
0
8
0
0
0
16
0
8
24
% T
% Val:
0
0
16
0
8
0
0
0
0
8
0
8
16
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _